HUWE1 Polyclonal Antibody, 20ul Variant Libraries Although this protein was earlier

Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP)

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This protein is highly similar to Saccharomyces cerevisiae Cdc 42

and tumor biology

HUWE1 Polyclonal Antibody, 20ul Variant Libraries Although this protein was earlierThis gene encodes a protein containing a C terminal HECT (E6AP type E3 ubiquitin protein ligase) domain that functions as an E3 ubiquitin ligase. The encoded protein is required for the ubiquitination and subsequent degradation of the anti apoptotic protein Mcl1 (myeloid cell leukemia sequence 1 (BCL2 related)). This protein also ubiquitinates the p53 tumor suppressor, core histones, and DNA polymerase beta. Mutations in this gene are associated with