Neu Polyclonal Antibody, 100ul[BT-AP05908] Mammalian Expression The N-end rule pathway is

The N-end rule pathway is one proteolytic pathway of the ubiquitin system

This protein displays E3 ubiquitin ligase activity toward the cyclin-dependent kinase inhibitor 1B which is also known as p27 or KIP1

but not in LoVo and HT-29 (colon adenocarcinoma)

Caffey Disease and idiopathic osteoporosis

Neu Polyclonal Antibody, 100ul[BT-AP05908] Mammalian Expression The N-end rule pathway isERBB2 encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. Receptor tyrosine protein kinase erbB 2 has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase mediated activation of downstream signalling pathways, such as those