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AGBL4 Polyclonal Antibody, 50ul Liquid Handling &Storage inhibiting oncogenic beta-catenin-mediated transcriptional activation

SKU: 96645697051

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AGBL4 Polyclonal Antibody, 50ul Liquid Handling &Storage inhibiting oncogenic beta-catenin-mediated transcriptional activationMetallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post translational polyglutamylation in proteins such as tubulins. Also removes gene encoded polyglutamates from the carboxy terminus of target proteins such as MYLK. Acts as a long chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point

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Description

inhibiting oncogenic beta-catenin-mediated transcriptional activation by competing with transcription factors for binding to beta-catenin

additional copies with truncations and internal deletions are also present in this region of chromosome 5q13

Among its related pathways are Gene Expression and Signaling by GPCR

CHAT encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine

AGBL4 Polyclonal Antibody, 50ul Liquid Handling &Storage inhibiting oncogenic beta-catenin-mediated transcriptional activationMetallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post translational polyglutamylation in proteins such as tubulins. Also removes gene encoded polyglutamates from the carboxy terminus of target proteins such as MYLK. Acts as a long chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point

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