HLA Class I Polyclonal Antibody, 100ul[BT-AP10062] Thermo Mix Mutations in this gene are

Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients

Alternative splicing of this gene generates three transcript variants encoding different isoforms

and it may also play a role in neuroimmune function

NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A)

HLA Class I Polyclonal Antibody, 100ul[BT-AP10062] Thermo Mix Mutations in this gene areHLA A belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta 2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon