MK12 Polyclonal Antibody, 100ul Recombinant Ab Production Defects in this gene are

Defects in this gene are a cause of hereditary coproporphyria (HCP)

The N-terminal domain of this protein is thought to mediate its association with SMG5 or UPF1 while the C-terminal domain interacts with the mRNA decay complex

and mutations in DYRK1B were found to cause abdominal obesity-metabolic syndrome 3

Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS)

MK12 Polyclonal Antibody, 100ul Recombinant Ab Production Defects in this gene areActivation of members of the mitogen activated protein kinase family is a major mechanism for transduction of extracellular signals. Stress activated protein kinases are one subclass of MAP kinases. The protein encoded by this gene functions as a signal transducer during differentiation of myoblasts to myotubes.