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FAK(Phospho Ser843) Polyclonal Antibody, 50ul Reservoirs The protein shares strong similarity

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FAK(Phospho Ser843) Polyclonal Antibody, 50ul Reservoirs The protein shares strong similarityThis gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal

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Description

The protein shares strong similarity with a Drosophila protein which interacts with the transcription factor disco and is expressed in the nervous system

It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients

the control of organ shape during development

Activation of CCND1 may be oncogenic by directly altering progression through the cell cycle

FAK(Phospho Ser843) Polyclonal Antibody, 50ul Reservoirs The protein shares strong similarityThis gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal

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