TIEG2 Polyclonal Antibody, 100ul Drug Development and Evaluation Mutations in this gene have

Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's fundus dystrophy

Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases

RNP1 and RNP2

The encoded enzyme contains a hydrolase domain at the N-terminal portion

TIEG2 Polyclonal Antibody, 100ul Drug Development and Evaluation Mutations in this gene haveKrueppel like factor 11 encoded by KLF11 is a zinc finger transcription factor that binds to SP1 like sequences in epsilon and gamma globin gene promoters. This binding inhibits cell growth and causes apoptosis. Defects in this gene are a cause of maturity onset diabetes of the young type 7 (MODY7). Three transcript variants encoding two different isoforms have been found for this gene.