MIB2 Polyclonal Antibody, 20ul Centrifugal Filter an N-linked glycan-processing enzyme in

an N-linked glycan-processing enzyme in the endoplasmic reticulum

and play a role in several developmental processes including early embryonic cell fate and organogenesis

and two beta subunits

This gene encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide

MIB2 Polyclonal Antibody, 20ul Centrifugal Filter an N-linked glycan-processing enzyme inE3 ubiquitin protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors.,induction: Down regulated in many primary skin melanomas. Treatment with a demethylating agent, 5' aza 2 deoxycytidine, restores expression, suggesting that down regulation is the result