CMBL Rabbit Polyclonal Antibody, 20ul Cell Culture Flasks displaying diverse cytoplasm-to-nucleus trafficking patterns

displaying diverse cytoplasm-to-nucleus trafficking patterns and distinct transcriptional activities (PMID:15866175)

which identify pathogen-associated molecular patterns

The first is an energy-independent docking of the protein to the nuclear envelope and the second is an energy-dependent translocation through the nuclear pore complex

Mutations in this gene are associated with lung cancer

CMBL Rabbit Polyclonal Antibody, 20ul Cell Culture Flasks displaying diverse cytoplasm-to-nucleus trafficking patternsCMBL (EC 3. 1. 1. 45) is a cysteine hydrolase of the dienelactone hydrolase family that is highly expressed in liver cytosol. CMBL preferentially cleaves cyclic esters and it activates medoxomil ester prodrugs in which the medoxomil moiety is linked to an oxygen atom (Ishizuka et al. 2010