Brigatinib-analog - CAS# 1197958-12-5 60061 105925-39-1

105925-39-1

CADTH Canadian Drug Expert Committee Recommendation: Obeticholic Acid (Ocaliva — Intercept Pharmaceuticals Canada): Indication: Primary biliary cholangitis [Internet]

Staurosporine slightly inhibits tumor promotion of Teleocidin

Stafford CA

Brigatinib-analog - CAS# 1197958-12-5 60061 105925-39-1Brigatinib analog, CAS No. 1197958 12 5, is an orally active, potent and selective anaplastic lymphoma kinase (ALK) and the epidermal growth factor receptor (EGFR) inhibitor. Brigatinib analog is structurally related to Brigatinib (AP 26113). Brigatinib analog binds to and inhibits ALK kinase and ALK fusion proteins as well as EGFR and mutant forms. This leads to the inhibition of ALK kinase and EGFR kinase, disrupts their signaling pathways and