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Lonafarnib - CAS# 193275-84-2 702 34)/b18-16+/t20-

Lonafarnib - CAS# 193275-84-2 702 34)/b18-16+/t20-

Name: Lonafarnib - CAS# 193275-84-2 702 34)/b18-16+/t20-
Brand: nyherosfund.org
SKU: 28633038125
Price: 113.05 USD
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SKU: 28633038125

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Lonafarnib - CAS# 193275-84-2 702 34)/b18-16+/t20-Lonafarnib is a farnesyl transferase inhibitor. Structurely, it is also a synthetic tricyclic derivative of carboxamide with antineoplastic properties. Lonarfanib binds to and inhibits farnesyl transferase, an enzyme involved in the post translational modification and activation of Ras proteins. Ras proteins participate in numerous signalling pathways (proliferation, cytoskeletal organization), and play an important role in oncogenesis. Mutated ras

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Description

34)/b18-16+/t20-

1380548-02-6

Metformin (500 μM) or AICAR strongly suppresses SREBP-1 mRNA expression in rat hepatocytes

At 5 μM it directly inhibits DUB activity of USP9x

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