Eltrombopag (Olamine) ntherin A CAS Number: 1355324-14-9

CAS Number: 1355324-14-9

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InChi: InChI=1S/C15H18O2/c1-8-4-7-12-10(3)15(16)17-14(12)13-9(2)5-6-11(8)13/h5

Eltrombopag (Olamine) ntherin A CAS Number: 1355324-14-9Eltrombopag is a small molecule, nonpeptide thrombopoietin receptor agonist with megakaryopoiesis stimulating activity. Eltrombopag binds to and stimulates the transmembrane domain of the platelet thrombopoietin receptor (TPO R or CD110), a member of the hematopoietin receptor superfamily. Activation of TPO R leads to the proliferation and differentiation of cells in the megakaryocytic lineage and an increase in platelet production. Eltrombopag was