Atovaquone yvitamin D3 in mice induces a rapid

in mice induces a rapid Akt phosphorylation readily detectable in lung lysates

For the convenience of scientific communication

MERcK-5 inhibits these kinases with IC50s ranging from 130 nM to >10 μM

5-trihydroxycyclohexane-1-carboxylic acid

Atovaquone yvitamin D3 in mice induces a rapidAtovaquone is a synthetic hydroxynaphthoquinone with antiprotozoal activity that has antimicrobial activity and is being used in antimalarial protocols. Atovoquone blocks the mitochondrial electron transport at complex III of the respiratory chain of protozoa, thereby inhibiting pyrimidine synthesis, preventing DNA synthesis and leading to protozoal death. It is an analog of protozoan mitochondrial protein ubiquinone, and acts by inhibiting the