AC55541 - CAS# 916170-19-9 size:2mg solid 331830-20-7

331830-20-7

epidermal growth factor receptor

Down-regulation and mutations of the nuclear-architecture proteins lamin A and C cause misshapen nuclei and altered chromatin organization associated with cancer and laminopathies

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AC55541 - CAS# 916170-19-9 size:2mg solid 331830-20-7AC 55541, CAS No. 916170 19 9, is a protease activated receptor (PAR) 2 agonist. AC 55541activated PAR2 signaling in cellular proliferation assays, phosphatidylinositol hydrolysis assays, and Ca(2+) mobilization assays, with potencies ranging from 200 to 1000 nM. AC 55541 was well absorbed when administered intraperitoneally to rats, each reaching micromolar peak plasma concentrations. AC 55541 was stable to metabolism by liver microsomes and