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JNJ-40411813 mifugin InChiKey: QOECJCJVIMVJGX-UHFFFAOYSA-N

JNJ-40411813 mifugin InChiKey: QOECJCJVIMVJGX-UHFFFAOYSA-N

Name: JNJ-40411813 mifugin InChiKey: QOECJCJVIMVJGX-UHFFFAOYSA-N
Brand: nyherosfund.org
SKU: 71434341206
Price: 155.00 USD
Availability: InStock
Rating: 4.2808 (23 reviews)

SKU: 71434341206

4.3

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JNJ-40411813 mifugin InChiKey: QOECJCJVIMVJGX-UHFFFAOYSA-NJNJ 40411813, also known as ADX71149, is a positive allosteric modulator of the mGlu2 receptor. JNJ 40411813 acts as a PAM at the cloned mGlu2 receptor: EC50 = 147 42 nmol L in a [(35)S]GTPS binding assay with human metabotropic glutamate type 2 (hmGlu2) CHO cells and EC50 = 64 29 nmol L in a Ca(2+) mobilization assay with hmGlu2 G 16 cotransfected HEK293 cells. JNJ 40411813 displaced [(3)H]JNJ 40068782 and [(3)H]JNJ 46281222 (mGlu2 receptor PAMs),

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Description

InChiKey: QOECJCJVIMVJGX-UHFFFAOYSA-N

InChi: InChI=1S/C24H23F3N4O2/c25-24(26

Biochim Biophys Acta

Chemical Name: 2-[4-(furan-2-carbonyl)piperazin-1-yl]-6

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