ML324 - JMJD2 Histone Demethylase Inhibitor. CAS# 1222800-79-4 size:10mg solid Ishizaki T
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ML324 - JMJD2 Histone Demethylase Inhibitor. CAS# 1222800-79-4 size:10mg solid Ishizaki TML324, CAS No. 1222800 79 4, is a potent, selective and cell permeable inhibitor of Jumonji domain containing protein 2 (JMJD2) histone demethylase with IC50 ~0. 92 M toward JMJD2E. It has excellent in vitro ADME properties, and it could effectively block both herpes simplex virus (HSV) and human cytomegalovirus (hCMV) infection via inhibition viral IE gene expression. ML324 suppresses the formation of HSV plaques, even at high MOI, and blocks HSV 1
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