SU14813 maleate - CAS# 849643-15-8 nalapril D5 maleate Formula: C23H31ClN4O3S
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SU14813 maleate - CAS# 849643-15-8 nalapril D5 maleate Formula: C23H31ClN4O3SSU14813 is an oral, multitargeted tyrosine kinase inhibitor (TKI) targeting vascular endothelial growth factor receptors (VEGFR), platelet derived growth factor receptors (PDGFR), KIT, and fms like tyrosine kinase 3 (FLT 3) (1). SU14813 was developed as a next generation TKI agent following sunitinib (SU11248) designed to demonstrate optimized pharmacokinetic (PK) and tolerability profiles. SU14813 demonstrated broad and potent antitumor activity
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