Tariquidar 126(ZZ) NSC-157035

NSC-157035

Atracurium is classified as an intermediate-duration non-depolarizing neuromuscular-blocking agent

in ACS Med Chem Lett

Smiles: CC1=CC2C(=CC=CC=2C(N)=O)N1C1=NC2CCOCC=2C(NCC2C=CC=CC=2)=N1

Tariquidar 126(ZZ) NSC-157035Tariquidar, also known as XR9576, is a P glycoprotein (P gp) inhibitor undergoing research as an adjuvant against multidrug resistance in cancer. Tariquidar non competitively binds to the p glycoprotein transporter, thereby inhibiting transmembrane transport of anticancer drugs. Inhibition of transmembrane transport may result in increased intracellular concentrations of an anticancer drug, thereby augmenting its cytotoxicity. Product information CAS