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Bazedoxifene acetate Catalog No.:M10044-2 TCS-JNK-6a binds competitively and reversibly

Bazedoxifene acetate Catalog No.:M10044-2 TCS-JNK-6a binds competitively and reversibly

Name: Bazedoxifene acetate Catalog No.:M10044-2 TCS-JNK-6a binds competitively and reversibly
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SKU: 84727722454
Price: 80.00 USD
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SKU: 84727722454

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Bazedoxifene acetate Catalog No.:M10044-2 TCS-JNK-6a binds competitively and reversiblyBazedoxifene, also known as WAY 140424, is a third generation selective estrogen receptor modulator (SERM), developed by Pfizer following the completion of their takeover of Wyeth Pharmaceuticals. In late 2013, Pfizer received approval for bazedoxifene as part of the combination drug DUAVEE in the prevention (not treatment) of postmenopausal osteoporosis. Bazedoxifene is an indole based ER ligand that binds to both ER (IC50 = 26 nM) and ER (IC50 = 99

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Description

TCS-JNK-6a binds competitively and reversibly to the ATP site

GDC-0068 was orally dosed to mice at 50-100 mg/kg once per day

1H2/b22-16+

ClH/c1-20-7-5-13(23-26-10-9-22)11-17(20)18(24)12-14-15-3-4-19(25)21(15

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