Caspase12 Polyclonal Antibody, 50ul miRNA / siRNA Synthesis The encoded protein may play

The encoded protein may play a role in spermatogenesis

The encoded protein downregulates apoptosis signal-regulating kinase 1

and is involved in translocation with the ets variant 6 gene in leukemia

PBK (PDZ binding kinase) encodes a serine/threonine protein kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family

Caspase12 Polyclonal Antibody, 50ul miRNA / siRNA Synthesis The encoded protein may playCaspases are cysteine proteases that cleave C terminal aspartic acid residues on their substrate molecules. CASP12 is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. In rodents, the homolog of CASP12 mediates apoptosis in response to endoplasmic reticulum stress. However, in humans CASP12 contains a polymorphism for the presence or absence of a premature stop codon. The majority of human individuals